Pediatric Neuro-Metabolic Test | Kite Health


The first-of-its-kind Pediatric Neuro-Metabolic Test uncovers gut–brain–immune imbalances in autism and ADHD by measuring microbial and immune metabolites in urine—with a stool add-on for deeper insights.

How the urine-based metabolic test works

Kite’s first test is a simple at-home urine test designed to give families a clearer picture of how a child’s body is functioning behind the scenes. Instead of focusing only on symptoms, the test looks at natural signals the body produces as it processes food, creates energy, and interacts with gut bacteria. These signals can help reveal patterns that may relate to common challenges families notice in everyday life—such as digestion issues, brain fog, low energy, mood changes, sleep difficulties, or reactions to certain foods. 

Kite’s first test is a simple at-home urine test designed to give families a clearer picture of how a child’s body is functioning behind the scenes. Instead of focusing only on symptoms, the test looks at natural signals the body produces as it processes food, creates energy, and interacts with gut bacteria. These signals can help reveal patterns that may relate to common challenges families notice in everyday life—such as digestion issues, brain fog, low energy, mood changes, sleep difficulties, or reactions to certain foods. 

The Kite platform then translates these results into clear, parent-friendly insights that connect what’s happening inside the body with what families observe day to day, helping parents and clinicians identify practical areas to explore together while tracking changes over time.

Why metabolites can be more actionable than microbe lists

Many tests look at one layer of biology. That information can be helpful, but it doesn’t always make the next step obvious for families.

Metabolite testing looks at what the body is actually doing right now. Instead of only identifying microbes, hormones, or nutrient levels, it measures the small molecules produced when the body digests food, produces energy, and interacts with gut microbes. These molecules—called metabolites—often provide a clearer signal about which biological pathways may need support (Tomar, Manendra S. et al. 2025).

Kite uses this functional approach to support a repeatable sequence: start with symptoms, interpret signals in context (diet, meds/supplements, illness, sleep debt), choose low-risk actions first, and track change. Because metabolites can shift with diet, stress, antibiotics, and sleep disruption, longitudinal tracking is built into the product.

 What we measure

1
Neurotransmitter-related metabolites (contextual)

Select metabolites can be interpreted as contextual signals related to neurotransmitter pathways, supporting clinician discussions about mood, focus, and sleep.

2
Microbial metabolites + dysbiosis patterns

Markers associated with microbial metabolism can align with GI symptoms and guide gut-support priorities, especially after antibiotics or recurring infections.

3
Carbohydrate metabolism & glycolysis

Markers related to carbohydrate processing can help contextualize blood sugar swings, energy dips, and post-meal dysregulation patterns.

4
 Fatty acid and ketone metabolism

Markers related to fatty acid metabolism can support conversations about energy utilization, diet patterns, and metabolic stress signals.

5
Protein metabolism + B-vitamin cofactors

Certain organic acids reflect amino acid metabolism and functional demand for B-vitamin cofactors—relevant when diets are restricted or symptoms suggest nutrient strain.

6
Citric Acid Cycle (CAC) metabolites (energy)

CAC intermediates provide a window into mitochondrial energy pathways—often important when fatigue, low stamina, or stress intolerance amplify behavior and mood challenges.

Why Gut–Brain Matters in Autism and ADHD

Research shows that many autistic children and those with ADHD present with:
Microbial shifts

fewer supportive species and more irritant-producers.

Immune footprints in urine

para-cresol, kynurenine detours, oxidative stress markers tied to sleep and behavior.

Bile acid imbalances

more primary bile acids, fewer microbial byproducts, suggesting inflammation and reduced diversity.

These patterns don’t “cause” autism or ADHD, but they can amplify challenges like tummy pain, sensory overload, or poor sleep.

Why Urine?

Stool tests measure what is in the microbiome, but urine shows the aftermath—tiny chemical traces of microbial activity, inflammation, and nutrient use. It’s painless, child-friendly, and powerful.

With the Neuro-Metabolic Test, Kite Health measures 100+ energy, nutrional and microbial metabolites grouped into clear “clues”:
Signal in Urine
Carbohydrate metabolism & glycolysis
Fatty acid and ketone metabolism
Protein metabolism + B-vitamin cofactors
Citric Acid Cycle (CAC) metabolites (energy)
Neurotransmitter-related metabolites (contextual)
Microbial metabolites + dysbiosis patterns
what they do
Markers related to carbohydrate processing can help contextualize blood sugar swings, energy dips, and post-meal dysregulation patterns.
Markers related to fatty acid metabolism can support conversations about energy utilization, diet patterns, and metabolic stress signals.
High immune-driven oxidative damage
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)

Why families like yours are essential

Kids on the autism spectrum have unique biology that standard adult lab tests miss. Without data from the right families:
1
Targeted food plans (fiber for missing microbes, oxalate-lowering diets, etc).
2
Strain-specific probiotic.  Unlimited cards
3
Nutrient support (B6, B12, antioxidants, etc).
4
Lifestyle tweaks to calm the gut–brain–immune loop.

Stool Add-On: Where to act in the Neighborhood?

For families or practitioners who want a deeper look at the gut’s residents, Kite offers a stool metabolomics add-on.
For families or practitioners who want a deeper look at the gut’s residents, Kite offers a stool metabolomics add-on.

While urine shows what’s happening chemically, stool reveals where to act in the gut. The stool kit checks for:
SCFA production and balance – “fuel” for the gut lining and immune system.
Nontoxicity – whether microbes are producing irritants.
Stability – whether microbes are producing irritants.
Unlimited cards

What this test can and cannot do

The Kite Neuro-Metabolic Test is designed to inform wellness decisions and clinician conversations. It cannot diagnose autism, ADHD, PANS/PANDAS, or any disorder or disease. It can provide a functional snapshot that helps prioritize next steps, reduce guesswork, and support tracking over time.

Why it’s next generation:

Deeper coverage
More biomarkers than other panels.
Faster turnaround
2× quicker than legacy workflows.
Neurodevelopment focus
Results linked to behaviors families actually see.
Child-friendly
Simple urine strip; optional stool for more insight.
The result: Unprecedented clarity—no guesswork, no extra kits, just actionable insight where gut, immune response, metabolism, and brain meet.

FAQ

Is this the same as microbiome sequencing?

No. Sequencing identifies microbes present. Kite’s body chemistry style approach measures metabolite outputs that reflect functional activity and can be easier to translate into interventions.

Can results change quickly?

Yes. Diet, illness, antibiotics, supplements, sleep disruption, and stress can shift metabolites—one reason tracking and intentional retesting can be valuable.

Why does Kite emphasize “foundation first”?

Because the safest, highest-impact actions for many families begin with basics like sleep consistency, hydration, constipation support, brain fog, and nutrient-dense foods before advanced protocols.

Still have questions?

Contact Us